IFIT2
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 555
应用备注
WB,1:500 - 1:2000
限制
仅限研究用
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
IFIT2
(Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))
别名
IFIT2
背景
IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism. Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.,IFIT2,G10P2,GARG-39,IFI-54,IFI-54K,IFI54,IFIT-2,ISG-54 K,ISG-54K,ISG54,P54,cig42,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,IFIT2