HSPA6 抗体 (AA 474-643)
Quick Overview for HSPA6 抗体 (AA 474-643) (ABIN6142046)
抗原
See all HSPA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 474-643
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序列
- PQIEVTFDID ANGILSVTAT DRSTGKANKI TITNDKGRLS KEEVERMVHE AEQYKAEDEA QRDRVAAKNS LEAHVFHVKG SLQEESLRDK IPEEDRRKMQ DKCREVLAWL EHNQLAEKEE YEHQKRELEQ ICRPIFSRLY GGPGVPGGSS CGTQARQGDP STGPIIEEVD
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 474-643 of human HSPA6 (NP_002146.2).
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亚型
- IgG
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anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) antibody
HSPA6 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) antibodyHSPA6 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) (Center) antibodyHSPA6 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) (AA 544-571), (C-Term) antibodyHSPA6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22779 unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) (AA 1-387) antibodyHSPA6 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) antibodyHSPA6 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) antibodyHSPA6 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) (AA 1-637) antibodyHSPA6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) (AA 544-643) antibodyHSPA6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6H7 unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) antibodyHSPA6 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 1E11 unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- HSPA6 (Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6))
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别名
- HSPA6
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背景
- Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release.,HSPA6,HSP70B,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,HSPA6
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分子量
- 71 kDa
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基因ID
- 3310
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UniProt
- P17066
抗原
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