HIRA 抗体 (AA 250-550)
Quick Overview for HIRA 抗体 (AA 250-550) (ABIN6141776)
抗原
See all HIRA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-550
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序列
- AQIIEREGWK TNMDFVGHRK AVTVVKFNPK IFKKKQKNGS SAKPSCPYCC CAVGSKDRSL SVWLTCLKRP LVVIHELFDK SIMDISWTLN GLGILVCSMD GSVAFLDFSQ DELGDPLSEE EKSRIHQSTY GKSLAIMTEA QLSTAVIENP EMLKYQRRQQ QQQLDQKSAA TREMGSATSV AGVVNGESLE DIRKNLLKKQ VETRTADGRR RITPLCIAQL DTGDFSTAFF NSIPLSGSLA GTMLSSHSSP QLLPLDSSTP NSFGASKPCT EPVVAASARP AGDSVNKDSM NATSTPAALS P
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 250-550 of human HIRA (NP_003316.3).
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亚型
- IgG
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anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibody
HIRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 1-1017) antibodyHIRA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (pThr555) antibodyHIRA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 374C6a unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 251-350) antibodyHIRA 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: Saccharomyces cerevisiae WB 宿主: 小鼠 Monoclonal 4B9 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 601-650) antibodyHIRA 适用: 人, 小鼠, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 421-729) antibodyHIRA 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal WC15 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 421-729) antibodyHIRA 适用: 人, 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal WC119-2H11 unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
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别名
- HIRA
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背景
- This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.,HIRA,DGCR1,TUP1,TUPLE1,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Cell Biology & Developmental Biology,Stem Cells,Germline Stem Cells,HIRA
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分子量
- 89 kDa/111 kDa
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基因ID
- 7290
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UniProt
- P54198
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途径
- Chromatin Binding
抗原
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