H2AFY 抗体 (AA 123-372)
Quick Overview for H2AFY 抗体 (AA 123-372) (ABIN6141569)
抗原
See all H2AFY 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 123-372
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序列
- KLEAIITPPP AKKAKSPSQK KPVSKKAGGK KGARKSKKKQ GEVSKAASAD STTEGTPADG FTVLSTKSLF LGQKLNLIHS EISNLAGFEV EAIINPTNAD IDLKDDLGNT LEKKGGKEFV EAVLELRKKN GPLEVAGAAV SAGHGLPAKF VIHCNSPVWG ADKCEELLEK TVKNCLALAD DKKLKSIAFP SIGSGRNGFP KQTAAQLILK AISSYFVSTM SSSIKTVYFV LFDSESIGIY VQEMAKLDAN
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 123-372 of human H2AFY (NP_613258.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- H2AFY (H2A Histone Family, Member Y (H2AFY))
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别名
- H2AFY
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背景
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.,H2AFY,H2A.y,H2A/y,H2AF12M,MACROH2A1.1,mH2A1,macroH2A1.2,Epigenetics & Nuclear Signaling,Histones,H2AFY
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分子量
- 39 kDa
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基因ID
- 9555
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UniProt
- O75367
抗原
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