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Metabotropic Glutamate Receptor 1 抗体 (AA 920-1140)

This anti-Metabotropic Glutamate Receptor 1 antibody is a 兔 多克隆 antibody detecting Metabotropic Glutamate Receptor 1 in WB. Suitable for 人.
产品编号 ABIN6141420
发货至: 中国

Quick Overview for Metabotropic Glutamate Receptor 1 抗体 (AA 920-1140) (ABIN6141420)

抗原

See all Metabotropic Glutamate Receptor 1 (GRM1) 抗体
Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Metabotropic Glutamate Receptor 1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 920-1140

    序列

    NETACNQTAV IKPLTKSYQG SGKSLTFSDT STKTLYNVEE EEDAQPIRFS PPGSPSMVVH RRVPSAATTP PLPSHLTAEE TPLFLAEPAL PKGLPPPLQQ QQQPPPQQKS LMDQLQGVVS NFSTAIPDFH AVLAGPGGPG NGLRSLYPPP PPPQHLQMLP LQLSTFGEEL VSPPADDDDD SERFKLLQEY VYEHEREGNT EEDELEEEEE DLQAASKLTP D

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 920-1140 of human GRM1 (NP_000829.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

    别名

    GRM1

    背景

    This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.,GRM1,GPRC1A,MGLU1,MGLUR1,PPP1R85,SCAR13,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,GRM1

    分子量

    101 kDa/132 kDa

    基因ID

    2911

    UniProt

    Q13255
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