Metabotropic Glutamate Receptor 1 抗体 (AA 920-1140)
Quick Overview for Metabotropic Glutamate Receptor 1 抗体 (AA 920-1140) (ABIN6141420)
抗原
See all Metabotropic Glutamate Receptor 1 (GRM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 920-1140
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序列
- NETACNQTAV IKPLTKSYQG SGKSLTFSDT STKTLYNVEE EEDAQPIRFS PPGSPSMVVH RRVPSAATTP PLPSHLTAEE TPLFLAEPAL PKGLPPPLQQ QQQPPPQQKS LMDQLQGVVS NFSTAIPDFH AVLAGPGGPG NGLRSLYPPP PPPQHLQMLP LQLSTFGEEL VSPPADDDDD SERFKLLQEY VYEHEREGNT EEDELEEEEE DLQAASKLTP D
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 920-1140 of human GRM1 (NP_000829.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
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别名
- GRM1
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背景
- This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.,GRM1,GPRC1A,MGLU1,MGLUR1,PPP1R85,SCAR13,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,GRM1
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分子量
- 101 kDa/132 kDa
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基因ID
- 2911
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UniProt
- Q13255
抗原
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