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GRIA4 抗体 (AA 254-433)

This anti-GRIA4 antibody is a 兔 多克隆 antibody detecting GRIA4 in WB. Suitable for 人.
产品编号 ABIN6141388
发货至: 中国

Quick Overview for GRIA4 抗体 (AA 254-433) (ABIN6141388)

抗原

See all GRIA4 抗体
GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

适用

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宿主

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克隆类型

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多克隆

标记

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This GRIA4 antibody is un-conjugated

应用范围

  • 57
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Western Blotting (WB)
  • 抗原表位

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    AA 254-433

    序列

    HGGANVTGFQ LVDFNTPMVI KLMDRWKKLD QREYPGSETP PKYTSALTYD GVLVMAETFR SLRRQKIDIS RRGNAGDCLA NPAAPWGQGI DMERTLKQVR IQGLTGNVQF DHYGRRVNYT MDVFELKSTG PRKVGYWNDM DKLVLIQDVP TLGNDTAAIE NRTVVVTTIM PLMKNPILRN

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 254-433 of human GluR4/GluA4/GluR4/GluA4/GRIA4 (NP_001070712.1).

    亚型

    IgG
  • 应用备注

    WB,1:1000 - 1:4000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

    别名

    GRIA4

    背景

    Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.,GRIA4,GLUR4,GLUR4C,GLURD,GluA4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Dopamine Signaling in Parkinson's Disease,GRIA4

    分子量

    49 kDa/100 kDa

    基因ID

    2893

    UniProt

    P48058

    途径

    PI3K-Akt Signaling
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