GRIA4 抗体 (AA 254-433)
Quick Overview for GRIA4 抗体 (AA 254-433) (ABIN6141388)
抗原
See all GRIA4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 254-433
-
序列
- HGGANVTGFQ LVDFNTPMVI KLMDRWKKLD QREYPGSETP PKYTSALTYD GVLVMAETFR SLRRQKIDIS RRGNAGDCLA NPAAPWGQGI DMERTLKQVR IQGLTGNVQF DHYGRRVNYT MDVFELKSTG PRKVGYWNDM DKLVLIQDVP TLGNDTAAIE NRTVVVTTIM PLMKNPILRN
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 254-433 of human GluR4/GluA4/GluR4/GluA4/GRIA4 (NP_001070712.1).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:1000 - 1:4000
-
说明
-
HIGH QUALITY
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
-
别名
- GRIA4
-
背景
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.,GRIA4,GLUR4,GLUR4C,GLURD,GluA4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Dopamine Signaling in Parkinson's Disease,GRIA4
-
分子量
- 49 kDa/100 kDa
-
基因ID
- 2893
-
UniProt
- P48058
-
途径
- PI3K-Akt Signaling
抗原
-