Glutamate Receptor 3 抗体 (AA 200-490)
Quick Overview for Glutamate Receptor 3 抗体 (AA 200-490) (ABIN6141386)
抗原
See all Glutamate Receptor 3 (GRIA3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-490
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序列
- QEFRRIIEEM DRRQEKRYLI DCEVERINTI LEQVVILGKH SRGYHYMLAN LGFTDILLER VMHGGANITG FQIVNNENPM VQQFIQRWVR LDEREFPEAK NAPLKYTSAL THDAILVIAE AFRYLRRQRV DVSRRGSAGD CLANPAVPWS QGIDIERALK MVQVQGMTGN IQFDTYGRRT NYTIDVYEMK VSGSRKAGYW NEYERFVPFS DQQISNDSAS SENRTIVVTT ILESPYVMYK KNHEQLEGNE RYEGYCVDLA YEIAKHVRIK YKLSIVGDGK YGARDPETKI W
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 200-490 of human GRIA3 (NP_000819.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))
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别名
- GRIA3
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背景
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.,GRIA3,GLUR-C,GLUR-K3,GLUR3,GLURC,GluA3,MRX94,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Dopamine Signaling in Parkinson's Disease,GRIA3
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分子量
- 101 kDa
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基因ID
- 2892
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UniProt
- P42263
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途径
- PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane
抗原
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