GP1BB 抗体 (AA 27-147)
Quick Overview for GP1BB 抗体 (AA 27-147) (ABIN6141287)
抗原
See all GP1BB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-147
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序列
- PAPCSCAGTL VDCGRRGLTW ASLPTAFPVD TTELVLTGNN LTALPPGLLD ALPALRTAHL GANPWRCDCR LVPLRAWLAG RPERAPYRDL RCVAPPALRG RLLPYLAEDE LRAACAPGPL C
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 27-147 of human GP1BB (NP_000398.1).
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亚型
- IgG
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anti-Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB) (AA 52-164) antibody
GP1BB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB) (AA 56-118) antibodyGP1BB 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB) (AA 53-176) antibodyGP1BB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB) (AA 27-147) antibodyGP1BB 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB) antibodyGP1BB 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB) (Internal Region) antibodyGP1BB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:200 - 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GP1BB (Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB))
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别名
- GP1BB
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背景
- Platelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain. Mutations in the GPIb beta subunit have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome and giant platelet disorder. The 206 amino acid precursor of GPIb beta is synthesized from a 1.0 kb mRNA expressed in plateletes and megakaryocytes. A 411 amino acid protein arising from a longer, unspliced transcript in endothelial cells has been described, however, the authenticity of this product has been questioned. Yet another less abundant GPIb beta mRNA species of 3.5 kb, expressed in nonhematopoietic tissues such as endothelium, brain and heart, was shown to result from inefficient usage of a non-consensus polyA signal in the neighboring upstream gene (SEPT5, septin 5). In the absence of polyadenylation from its own imperfect site, the SEPT5 gene produces read-through transcripts that use the consensus polyA signal of this gene.,GP1BB,BDPLT1,BS,CD42C,GPIBB,GPIbbeta,Immunology & Inflammation,CD markers,GP1BB
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分子量
- 21 kDa/43 kDa
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基因ID
- 2812
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UniProt
- P13224
抗原
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