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GNAS 抗体 (AA 1-394)

Name: GNAS 抗体 (AA 1-394)
Brand: antibodies-online
SKU: ABIN6141213
Availability: OutOfStock

This anti-GNAS antibody is a 兔多克隆 antibody detecting GNAS in WB, IF 和 IP. Suitable for 人.

Western blot analysis of extracts of various cell lines, using GNAS antibody (ABIN6127959, ABIN6141213, ABIN6141214 and ABIN6221191) at 1:1000 dilution. (GNAS 抗体 (AA 1-394))

Immunofluorescence analysis of L929 cells using GNAS Rabbit pAb (ABIN6127959, ABIN6141213, ABIN6141214 and ABIN6221191) at dilution of 1:100. (GNAS 抗体 (AA 1-394))

Immunoprecipitation analysis of 200 μg extracts of Mouse brain cells using 3 μg GNAS antibody (ABIN6127959, ABIN6141213, ABIN6141214 and ABIN6221191). (GNAS 抗体 (AA 1-394))

Immunofluorescence analysis of U2OS cells using GNAS Rabbit pAb (ABIN6127959, ABIN6141213, ABIN6141214 and ABIN6221191) at dilution of 1:100. (GNAS 抗体 (AA 1-394))

4 images

产品编号 ABIN6141213

发货至: 中国

Quick Overview for GNAS 抗体 (AA 1-394) (ABIN6141213)

抗原

See all GNAS 抗体

GNAS (GNAS Complex Locus (GNAS))

适用

人

宿主

兔

克隆类型

多克隆

标记

This GNAS antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Discover our top product GNAS Primary Antibody

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AA 1-394

序列

MGCLGNSKTE DQRNEEKAQR EANKKIEKQL QKDKQVYRAT HRLLLLGAGE SGKSTIVKQM RILHVNGFNG EGGEEDPQAA RSNSDGEKAT KVQDIKNNLK EAIETIVAAM SNLVPPVELA NPENQFRVDY ILSVMNVPDF DFPPEFYEHA KALWEDEGVR ACYERSNEYQ LIDCAQYFLD KIDVIKQADY VPSDQDLLRC RVLTSGIFET KFQVDKVNFH MFDVGGQRDE RRKWIQCFND VTAIIFVVAS SSYNMVIRED NQTNRLQEAL NLFKSIWNNR WLRTISVILF LNKQDLLAEK VLAGKSKIED YFPEFARYTT PEDATPEPGE DPRVTRAKYF IRDEFLRIST ASGDGRHYCY PHFTCAVDTE NIRRVFNDCR DIIQRMHLRQ YELL

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-394 of human GNAS (NP_000507.1).

亚型

IgG
anti-GNAS Complex Locus (GNAS) (AA 42-188) antibody
GNAS 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2A2B7 unconjugated

anti-GNAS Complex Locus (GNAS) (N-Term) antibody
GNAS 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) antibody
KO Validated GNAS 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 42-188) antibody
GNAS 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G6G5 unconjugated

anti-GNAS Complex Locus (GNAS) (N-Term) antibody
GNAS 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 310-404) antibody
GNAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (Internal Region) antibody
Verified GNAS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 287-315), (C-Term) antibody
GNAS 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33001 unconjugated

anti-GNAS Complex Locus (GNAS) (AA 286-315), (C-Term) antibody
GNAS 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 1-394) antibody
GNAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

说明

HIGH QUALITY

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
抗原

GNAS (GNAS Complex Locus (GNAS))

别名

GNAS

背景

This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.,GNAS,AHO,C20orf45,GNAS1,GPSA,GSA,GSP,NESP,POH,SCG6,SgVI,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Phospholipase Signaling Pathway,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,GNAS

分子量

28 kDa/44 kDa/45 kDa/77 kDa/109 kDa/111 kDa

基因ID

2778

UniProt

O95467, P63092, P84996, Q5JWF2

途径

Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis