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Geminin 抗体 (AA 1-209)

This anti-Geminin antibody is a 兔 多克隆 antibody detecting Geminin in WB 和 IHC. Suitable for 人.
产品编号 ABIN6141186
发货至: 中国

Quick Overview for Geminin 抗体 (AA 1-209) (ABIN6141186)

抗原

See all Geminin (GMNN) 抗体
Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

适用

  • 63
  • 13
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宿主

  • 50
  • 18

克隆类型

  • 46
  • 22
多克隆

标记

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This Geminin antibody is un-conjugated

应用范围

  • 34
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 11
    • 7
    • 3
    • 2
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    • 1
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    AA 1-209

    序列

    MNPSMKQKQE EIKENIKNSS VPRRTLKMIQ PSASGSLVGR ENELSAGLSK RKHRNDHLTS TTSSPGVIVP ESSENKNLGG VTQESFDLMI KENPSSQYWK EVAEKRRKAL YEALKENEKL HKEIEQKDNE IARLKKENKE LAEVAEHVQY MAELIERLNG EPLDNFESLD NQEFDSEEET VEDSLVEDSE IGTCAEGTVS SSTDAKPCI

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human GMNN (NP_056979.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

    别名

    GMNN

    背景

    This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.,GMNN,Gem,MGORS6,geminin,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,GMNN

    分子量

    23 kDa

    基因ID

    51053

    UniProt

    O75496

    途径

    EGFR Signaling Pathway, DNA Replication
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