GLYR1 抗体 (AA 70-270)
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北京 101111
Quick Overview for GLYR1 抗体 (AA 70-270) (ABIN6141170)
抗原
See all GLYR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-270
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序列
- MIKINKGKRF QQAVDAVEEF LRRAKGKDQT SSHNSSDDKN RRNSSEERSR PNSGDEKRKL SLSEGKVKKN MGEGKKRVSS GSSERGSKSP LKRAQEQSPR KRGRPPKDEK DLTIPESSTV KGMMAGPMAA FKWQPTASEP VKDADPHFHH FLLSQTEKPA VCYQAITKKL KICEEETGST SIQAADSTAV NGSITPTDKK I
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 70-270 of human GLYR1 (NP_115958.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))
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别名
- GLYR1
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背景
- Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation. Facilitates Pol II transcription through nucleosomes. Binds DNA (in vitro. Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3. Promotes KDM1B demethylase activity. Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac by EP300. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Putative oxidoreductase.,GLYR1,BM045,HIBDL,N-PAC,NP60,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,GLYR1
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分子量
- 51 kDa/52 kDa/58 kDa/59 kDa/60 kDa
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基因ID
- 84656
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UniProt
- Q49A26
抗原
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