GLYR1
适用: 人, 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
FITC
应用备注
WB,1:500 - 1:2000,IHC,1:100 - 1:200
限制
仅限研究用
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
GLYR1
(Glyoxylate Reductase 1 Homolog (GLYR1))
别名
GLYR1
背景
Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation. Facilitates Pol II transcription through nucleosomes. Binds DNA (in vitro. Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3. Promotes KDM1B demethylase activity. Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac by EP300. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Putative oxidoreductase.,GLYR1,BM045,HIBDL,N-PAC,NP60,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,GLYR1