GLDC 抗体 (AA 36-290)
Quick Overview for GLDC 抗体 (AA 36-290) (ABIN6141119)
抗原
See all GLDC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 36-290
-
序列
- DSSSGGGDSA AAGASRLLER LLPRHDDFAR RHIGPGDKDQ REMLQTLGLA SIDELIEKTV PANIRLKRPL KMEDPVCENE ILATLHAISS KNQIWRSYIG MGYYNCSVPQ TILRNLLENS GWITQYTPYQ PEVSQGRLES LLNYQTMVCD ITGLDMANAS LLDEGTAAAE ALQLCYRHNK RRKFLVDPRC HPQTIAVVQT RAKYTGVLTE LKLPCEMDFS GKDVSGVLFQ YPDTEGKVED FTELVERAHQ SGSLA
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 36-290 of human GLDC (NP_000161.2).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100,IP,1:50 - 1:200
-
说明
-
HIGH QUALITY
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- GLDC (Glycine Dehydrogenase (GLDC))
-
别名
- GLDC
-
背景
- Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).,GLDC,GCE,GCSP,HYGN1,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,GLDC
-
分子量
- 112 kDa
-
基因ID
- 2731
-
UniProt
- P23378
抗原
-