Ghrelin 抗体 (AA 1-117)
Quick Overview for Ghrelin 抗体 (AA 1-117) (ABIN6141079)
抗原
See all Ghrelin (GHRL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-117
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序列
- MPSPGTVCSL LLLGMLWLDL AMAGSSFLSP EHQRVQQRKE SKKPPAKLQP RALAGWLRPE DGGQAEGAED ELEVRFNAPF DVGIKLSGVQ YQQHSQALGK FLQDILWEEA KEAPADK
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交叉反应
- 人, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-117 of human GHRL (NP_057446.1).
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亚型
- IgG
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anti-Ghrelin (GHRL) (AA 1-117) antibody
GHRL 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Ghrelin (GHRL) (AA 28-117) antibodyGHRL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) antibodyGHRL 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (AA 25-117) antibodyGHRL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (C-Term) antibodyVerified GHRL 适用: 人, 大鼠 ELISA, IHC, ICC 宿主: 山羊 Polyclonal unconjugated
anti-Ghrelin (GHRL) (AA 31-117) antibodyGHRL 适用: 人, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (AA 1-117) antibodyGHRL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (C-Term) antibodyGHRL 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (AA 1-118) antibodyGHRL 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Ghrelin (GHRL) (AA 24-117) antibodyGHRL 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F2 unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Ghrelin (GHRL)
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别名
- GHRL
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背景
- This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.,GHRL,MTLRP,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Obesity,Neuroscience,Cardiovascular,Blood,Heart,Cardiovascular diseases,Heart disease,GHRL
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分子量
- 7 kDa/9 kDa/11 kDa/12 kDa
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基因ID
- 51738
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UniProt
- Q9UBU3
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour
抗原
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