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GDF5 抗体 (AA 350-450)

This anti-GDF5 antibody is a 兔 多克隆 antibody detecting GDF5 in WB 和 IHC. Suitable for 人.
产品编号 ABIN6141044
发货至: 中国

Quick Overview for GDF5 抗体 (AA 350-450) (ABIN6141044)

抗原

See all GDF5 抗体
GDF5 (Growth Differentiation Factor 5 (GDF5))

适用

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  • 42
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宿主

  • 89
  • 5
  • 3
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  • 1

克隆类型

  • 93
  • 8
多克隆

标记

  • 44
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  • 9
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  • 2
  • 2
  • 2
  • 2
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  • 1
  • 1
  • 1
  • 1
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This GDF5 antibody is un-conjugated

应用范围

  • 75
  • 46
  • 35
  • 20
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  • 9
  • 9
  • 5
  • 4
  • 4
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  • 2
  • 2
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 11
    • 8
    • 8
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
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    • 1
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    • 1
    AA 350-450

    序列

    KRDLFFNEIK ARSGQDDKTV YEYLFSQRRK RRAPLATRQG KRPSKNLKAR CSRKALHVNF KDMGWDDWII APLEYEAFHC EGLCEFPLRS HLEPTNHAVI Q

    交叉反应

    小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 350-450 of human GDF5 (NP_000548.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GDF5 (Growth Differentiation Factor 5 (GDF5))

    别名

    GDF5

    背景

    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis.,GDF5,BDA1C,BMP-14,BMP14,CDMP1,LAP-4,LAP4,OS5,SYM1B,SYNS2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Immunology & Inflammation,Cytokines,Stem Cells,Cardiovascular,Angiogenesis,GDF5

    分子量

    55 kDa

    基因ID

    8200

    UniProt

    P43026
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