GCKR 抗体 (AA 1-300)
Quick Overview for GCKR 抗体 (AA 1-300) (ABIN6141014)
抗原
See all GCKR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-300
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序列
- MPGTKRFQHV IETPEPGKWE LSGYEAAVPI TEKSNPLTQD LDKADAENIV RLLGQCDAEI FQEEGQALST YQRLYSESIL TTMVQVAGKV QEVLKEPDGG LVVLSGGGTS GRMAFLMSVS FNQLMKGLGQ KPLYTYLIAG GDRSVVASRE GTEDSALHGI EELKKVAAGK KRVIVIGISV GLSAPFVAGQ MDCCMNNTAV FLPVLVGFNP VSMARNDPIE DWSSTFRQVA ERMQKMQEKQ KAFVLNPAIG PEGLSGSSRM KGGSATKILL ETLLLAAHKT VDQGIAASQR CLLEILRTFE
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GCKR (NP_001477.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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别名
- GCKR
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背景
- This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).,GCKR,FGQTL5,GKRP,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,GCKR
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分子量
- 16 kDa/68 kDa
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基因ID
- 2646
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UniProt
- Q14397
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途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
抗原
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