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GALE 抗体 (AA 129-348)

This anti-GALE antibody is a 兔 多克隆 antibody detecting GALE in WB 和 IHC. Suitable for 人.
产品编号 ABIN6140933
发货至: 中国

Quick Overview for GALE 抗体 (AA 129-348) (ABIN6140933)

抗原

See all GALE 抗体
GALE (UDP-Galactose-4-Epimerase (GALE))

适用

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宿主

  • 47
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克隆类型

  • 49
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多克隆

标记

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This GALE antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 129-348

    序列

    FSSSATVYGN PQYLPLDEAH PTGGCTNPYG KSKFFIEEMI RDLCQADKTW NAVLLRYFNP TGAHASGCIG EDPQGIPNNL MPYVSQVAIG RREALNVFGN DYDTEDGTGV RDYIHVVDLA KGHIAALRKL KEQCGCRIYN LGTGTGYSVL QMVQAMEKAS GKKIPYKVVA RREGDVAACY ANPSLAQEEL GWTAALGLDR MCEDLWRWQK QNPSGFGTQA

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 129-348 of human GALE (NP_001121093.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GALE (UDP-Galactose-4-Epimerase (GALE))

    别名

    GALE

    背景

    This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.,GALE,SDR1E1,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,GALE

    分子量

    30 kDa/38 kDa

    基因ID

    2582

    UniProt

    Q14376

    途径

    Response to Water Deprivation, Cellular Glucan Metabolic Process
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