FUS 抗体 (AA 297-526)
Quick Overview for FUS 抗体 (AA 297-526) (ABIN6140818)
抗原
See all FUS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 297-526
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序列
- TIESVADYFK QIGIIKTNKK TGQPMINLYT DRETGKLKGE ATVSFDDPPS AKAAIDWFDG KEFSGNPIKV SFATRRADFN RGGGNGRGGR GRGGPMGRGG YGGGGSGGGG RGGFPSGGGG GGGQQRAGDW KCPNPTCENM NFSWRNECNQ CKAPKPDGPG GGPGGSHMGG NYGDDRRGGR GGYDRGGYRG RGGDRGGFRG GRGGGDRGGF GPGKMDSRGE HRQDRRERPY
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 297-526 of human FUS (NP_004951.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100,IP,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- FUS (Fused in Sarcoma (FUS))
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别名
- FUS
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背景
- This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.,FUS,ALS6,ETM4,FUS1,HNRNPP2,POMP75,TLS,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Cancer,Signal Transduction,FUS
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分子量
- 53 kDa
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基因ID
- 2521
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UniProt
- P35637
抗原
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