FUBP1 抗体 (AA 302-644)
Quick Overview for FUBP1 抗体 (AA 302-644) (ABIN6140802)
抗原
See all FUBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 302-644
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序列
- QNDAGVRIQF KPDDGTTPER IAQITGPPDR CQHAAEIITD LLRSVQAGNP GGPGPGGRGR GRGQGNWNMG PPGGLQEFNF IVPTGKTGLI IGKGGETIKS ISQQSGARIE LQRNPPPNAD PNMKLFTIRG TPQQIDYARQ LIEEKIGGPV NPLGPPVPHG PHGVPGPHGP PGPPGPGTPM GPYNPAPYNP GPPGPAPHGP PAPYAPQGWG NAYPHWQQQA PPDPAKAGTD PNSAAWAAYY AHYYQQQAQP PPAAPAGAPT TTQTNGQGDQ QNPAPAGQVD YTKAWEEYYK KMGQAVPAPT GAPPGGQPDY SAAWAEYYRQ QAAYYAQTSP QGMPQHPPAP QGQ
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 302-644 of human FUBP1 (NP_003893.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100,IP,1:50 - 1:100
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))
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别名
- FUBP1
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背景
- The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants.,FUBP1,FBP,FUBP,hDH V,hDHV,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,FUBP1
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分子量
- 67 kDa/68 kDa
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基因ID
- 8880
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UniProt
- Q96AE4
抗原
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