FOXP2 抗体 (AA 441-740)
Quick Overview for FOXP2 抗体 (AA 441-740) (ABIN6140762)
抗原
See all FOXP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 441-740
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序列
- PKPSPKPLNL VSSVTMSKNM LETSPQSLPQ TPTTPTAPVT PITQGPSVIT PASVPNVGAI RRRHSDKYNI PMSSEIAPNY EFYKNADVRP PFTYATLIRQ AIMESSDRQL TLNEIYSWFT RTFAYFRRNA ATWKNAVRHN LSLHKCFVRV ENVKGAVWTV DEVEYQKRRS QKITGSPTLV KNIPTSLGYG AALNASLQAA LAESSLPLLS NPGLINNASS GLLQAVHEDL NGSLDHIDSN GNSSPGCSPQ PHIHSIHVKE EPVIAEDEDC PMSLVTTANH SPELEDDREI EEEPLSEDLE
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 441-740 of human FOXP2 (NP_683696.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- FOXP2 (Forkhead Box P2 (FOXP2))
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别名
- FOXP2
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背景
- This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.,FOXP2,CAGH44,SPCH1,TNRC10,Epigenetics & Nuclear Signaling,Transcription Factors,FOXP2
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分子量
- 9-18 kDa/40- 48 kDa/70- 82 kDa
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基因ID
- 93986
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UniProt
- O15409
抗原
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