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ETV1 抗体 (AA 1-200)

This anti-ETV1 antibody is a 兔 多克隆 antibody detecting ETV1 in WB 和 IF. Suitable for 人.
产品编号 ABIN6140328
发货至: 中国

Quick Overview for ETV1 抗体 (AA 1-200) (ABIN6140328)

抗原

See all ETV1 抗体
ETV1 (Ets Variant 1 (ETV1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ETV1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-200

    序列

    MDGFYDQQVP YMVTNSQRGR NCNEKPTNVR KRKFINRDLA HDSEELFQDL SQLQETWLAE AQVPDNDEQF VPDYQAESLA FHGLPLKIKK EPHSPCSEIS SACSQEQPFK FSYGEKCLYN VSAYDQKPQV GMRPSNPPTP SSTPVSPLHH ASPNSTHTPK PDRAFPAHLP PSQSIPDSSY PMDHRFRRQL SEPCNSFPPL

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human ETV1 (NP_004947.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ETV1 (Ets Variant 1 (ETV1))

    别名

    ETV1

    背景

    This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.,ETV1,ER81,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Neuroscience,Stem Cells,Hematopoietic Progenitors,ETV1

    分子量

    43 kDa/48 kDa/50 kDa/52 kDa/53 kDa/55 kDa

    基因ID

    2115

    UniProt

    P50549
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