ELANE 抗体 (AA 30-267)
Quick Overview for ELANE 抗体 (AA 30-267) (ABIN6140110)
抗原
See all ELANE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-267
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序列
- IVGGRRARPH AWPFMVSLQL RGGHFCGATL IAPNFVMSAA HCVANVNVRA VRVVLGAHNL SRREPTRQVF AVQRIFENGY DPVNLLNDIV ILQLNGSATI NANVQVAQLP AQGRRLGNGV QCLAMGWGLL GRNRGIASVL QELNVTVVTS LCRRSNVCTL VRGRQAGVCF GDSGSPLVCN GLIHGIASFV RGGCASGLYP DAFAPVAQFV NWIDSIIQRS EDNPCPHPRD PDPASRTH
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 30-267 of human Neutrophil Elastase (ELANE) (NP_001963.1).
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亚型
- IgG
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anti-Elastase, Neutrophil Expressed (ELANE) (AA 140-267) antibody
ELANE 适用: 人, 猴 ELISA, WB, IHC, FACS 宿主: 小鼠 Monoclonal 6B6B10 unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-247) antibodyELANE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 140-267) antibodyELANE 适用: 人, 大鼠 ELISA, WB, FACS 宿主: 小鼠 Monoclonal 6B6G6 unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-267) antibodyELANE 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 ELISA, IHC, FACS 宿主: 兔 Monoclonal 2H12 unconjugated Recombinant Antibody
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 168-267) antibodyELANE 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 27-265) antibodyELANE 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 29-247) antibodyELANE 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ELANE (Elastase, Neutrophil Expressed (ELANE))
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别名
- ELANE
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背景
- Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19.,ELANE,ELA2,GE,HLE,HNE,NE,PMN-E,SCN1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,ELANE
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分子量
- 28 kDa
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基因ID
- 1991
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UniProt
- P08246
抗原
-
