EIF3C 抗体 (AA 694-913)
Quick Overview for EIF3C 抗体 (AA 694-913) (ABIN6140055)
抗原
See all EIF3C 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 694-913
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                                            序列
- EIPYMAAHES DARRRMISKQ FHHQLRVGER QPLLGPPESM REHVVAASKA MKMGDWKTCH SFIINEKMNG KVWDLFPEAD KVRTMLVRKI QEESLRTYLF TYSSVYDSIS METLSDMFEL DLPTVHSIIS KMIINEELMA SLDQPTQTVV MHRTEPTAQQ NLALQLAEKL GSLVENNERV FDHKQGTYGG YFRDQKDGYR KNEGYMRRGG YRQQQSQTAY
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            产品特性
- Polyclonal Antibodies
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                                            纯化方法
- Affinity purification
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                                            免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 694-913 of human EIF3C (NP_003743.1).
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                                            亚型
- IgG
 
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    - 
                                            应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100
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                                            说明
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                        HIGH QUALITY 
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))
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                                            别名
- EIF3C
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                                            背景
- Component of the eukaryotic translation initiation factor 3 (eIF-3 complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC. The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.,EIF3C,EIF3CL,EIF3S8,eIF3-p110,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,EIF3C
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                                            分子量
- 104 kDa/105 kDa
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                                            基因ID
- 8663
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                                            UniProt
- Q99613
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                                            途径
- Ribonucleoprotein Complex Subunit Organization
 抗原
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