Desmoglein 1 抗体 (AA 800-1049)
Quick Overview for Desmoglein 1 抗体 (AA 800-1049) (ABIN6139829)
抗原
See all Desmoglein 1 (DSG1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 800-1049
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序列
- SPHFGTTTVI SESTYPSGPG VLHPKPILDP LGYGNVTVTE SYTTSDTLKP SVHVHDNRPA SNVVVTERVV GPISGADLHG MLEMPDLRDG SNVIVTERVI APSSSLPTSL TIHHPRESSN VVVTERVIQP TSGMIGSLSM HPELANAHNV IVTERVVSGA GVTGISGTTG ISGGIGSSGL VGTSMGAGSG ALSGAGISGG GIGLSSLGGT ASIGHMRSSS DHHFNQTIGS ASPSTARSRI TKYSTVQYSK
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交叉反应
- 人, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 800-1049 of human DSG1 (NP_001933.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Desmoglein 1 (DSG1)
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别名
- DSG1
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背景
- This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.,DSG1,CDHF4,DG1,DSG,EPKHE,EPKHIA,PPKS1,SPPK1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cytoskeleton,Neuroscience,Calcium Signaling,DSG1
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分子量
- 42 kDa/113 kDa
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基因ID
- 1828
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UniProt
- Q02413
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途径
- Cell-Cell Junction Organization
抗原
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