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Desmoglein 1 抗体 (AA 800-1049)

This anti-Desmoglein 1 antibody is a 兔 多克隆 antibody detecting Desmoglein 1 in WB 和 IF. Suitable for 人.
产品编号 ABIN6139829
发货至: 中国

Quick Overview for Desmoglein 1 抗体 (AA 800-1049) (ABIN6139829)

抗原

See all Desmoglein 1 (DSG1) 抗体
Desmoglein 1 (DSG1)

适用

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宿主

  • 62
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克隆类型

  • 56
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多克隆

标记

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This Desmoglein 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 800-1049

    序列

    SPHFGTTTVI SESTYPSGPG VLHPKPILDP LGYGNVTVTE SYTTSDTLKP SVHVHDNRPA SNVVVTERVV GPISGADLHG MLEMPDLRDG SNVIVTERVI APSSSLPTSL TIHHPRESSN VVVTERVIQP TSGMIGSLSM HPELANAHNV IVTERVVSGA GVTGISGTTG ISGGIGSSGL VGTSMGAGSG ALSGAGISGG GIGLSSLGGT ASIGHMRSSS DHHFNQTIGS ASPSTARSRI TKYSTVQYSK

    交叉反应

    人, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 800-1049 of human DSG1 (NP_001933.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Desmoglein 1 (DSG1)

    别名

    DSG1

    背景

    This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.,DSG1,CDHF4,DG1,DSG,EPKHE,EPKHIA,PPKS1,SPPK1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cytoskeleton,Neuroscience,Calcium Signaling,DSG1

    分子量

    42 kDa/113 kDa

    基因ID

    1828

    UniProt

    Q02413

    途径

    Cell-Cell Junction Organization
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