Dopamine d2 Receptor 抗体 (AA 214-373)
Quick Overview for Dopamine d2 Receptor 抗体 (AA 214-373) (ABIN6139821)
抗原
See all Dopamine d2 Receptor (DRD2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 214-373
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序列
- IVLRRRRKRV NTKRSSRAFR AHLRAPLKGN CTHPEDMKLC TVIMKSNGSF PVNRRRVEAA RRAQELEMEM LSSTSPPERT RYSPIPPSHH QLTLPDPSHH GLHSTPDSPA KPEKNGHAKD HPKIAKIFEI QTMPNGKTRT SLKTMSRRKL SQQKEKKATQ
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 214-373 of human DRD2 (NP_000786.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))
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别名
- DRD2
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背景
- This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia, other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.,DRD2,D2DR,D2R,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Neuron marker,Dendrite marker,DRD2
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分子量
- 47 kDa/50 kDa
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基因ID
- 1813
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UniProt
- P14416
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途径
- Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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