DPPA4 抗体 (AA 15-304)
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北京 101111
Quick Overview for DPPA4 抗体 (AA 15-304) (ABIN6139802)
抗原
See all DPPA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-304
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序列
- KGKEWTSTEK SREEDQQASN QPNSIALPGT SAKRTKEKMS IKGSKVLCPK KKAEHTDNPR PQKKIPIPPL PSKLPPVNLI HRDILRAWCQ QLKLSSKGQK LDAYKRLCAF AYPNQKDFPS TAKEAKIRKS LQKKLKVEKG ETSLQSSETH PPEVALPPVG EPPALENSTA LLEGVNTVVV TTSAPEALLA SWARISARAR TPEAVESPQE ASGVRWCVVH GKSLPADTDG WVHLQFHAGQ AWVPEKQEGR VSALFLLPAS NFPPPHLEDN MLCPKCVHRN KVLIKSLQWE
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 15-304 of human DPPA4 (NP_060659.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))
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别名
- DPPA4
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背景
- This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.,DPPA4,2410091M23Rik,Cell Biology & Developmental Biology,Stem Cells,Embryonic Stem Cells,DPPA4
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分子量
- 33 kDa
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基因ID
- 55211
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UniProt
- Q7L190
抗原
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