DLAT 抗体 (AA 1-290)
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北京 101111
Quick Overview for DLAT 抗体 (AA 1-290) (ABIN6139639)
抗原
See all DLAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-290
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序列
- MWRVCARRAQ NVAPWAGLEA RWTALQEVPG TPRVTSRSGP APARRNSVTT GYGGVRALCG WTPSSGATPR NRLLLQLLGS PGRRYYSLPP HQKVPLPSLS PTMQAGTIAR WEKKEGDKIN EGDLIAEVET DKATVGFESL EECYMAKILV AEGTRDVPIG AIICITVGKP EDIEAFKNYT LDSSAAPTPQ AAPAPTPAAT ASPPTPSAQA PGSSYPPHMQ VLLPALSPTM TMGTVQRWEK KVGEKLSEGD LLAEIETDKA TIGFEVQEEG YLAKILVPEG TRDVPLGTPL
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human DLAT (NP_001922.2).
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亚型
- IgG
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anti-Dihydrolipoyl Transacetylase (DLAT) (AA 368-626) antibody
DLAT 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 87-270) antibodyDLAT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) antibodyDLAT 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 1-647) antibodyDLAT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 1-647) antibodyDLAT 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) antibodyKD Validated DLAT 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB805 unconjugated Recombinant Antibody
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 579-607), (C-Term) antibodyDLAT 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26843 unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (N-Term) antibodyDLAT 适用: 人, 小鼠, 大鼠, 兔, 犬, 斑马鱼, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 26-217) antibodyDLAT 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) antibodyDLAT 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:20 - 1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- DLAT (Dihydrolipoyl Transacetylase (DLAT))
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别名
- DLAT
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背景
- This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95 % of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.,DLAT,DLTA,PDC-E2,PDCE2,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Carbohydrate metabolism,DLAT
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分子量
- 68 kDa
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基因ID
- 1737
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UniProt
- P10515
抗原
-
