DBNL
适用: 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
Cy3
应用备注
WB,1:500 - 1:2000,IF,1:50 - 1:100
限制
仅限研究用
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
DBNL
(Drebrin-Like (DBNL))
别名
DBNL
背景
Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.,DBNL,ABP1,HIP-55,HIP55,SH3P7,Signal Transduction,DBNL