DAZL 抗体 (AA 186-295)
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北京 101111
Quick Overview for DAZL 抗体 (AA 186-295) (ABIN6139416)
抗原
See all DAZL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 186-295
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序列
- VYNYQMPPQW PVGEQRSYVV PPAYSAVNYH CNEVDPGAEV VPNECSVHEA TPPSGNGPQK KSVDRSIQTV VSCLFNPENR LRNSVVTQDD YFKDKRVHHF RRSRAMLKSV
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 186-295 of human DAZL (NP_001342.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- DAZL (Deleted in Azoospermia-Like (DAZL))
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别名
- DAZL
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背景
- The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.,DAZL,DAZH,DAZL1,DAZLA,SPGYLA,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Stem Cells,Germline Stem Cells,DAZL
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分子量
- 33 kDa/35 kDa
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基因ID
- 1618
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UniProt
- Q92904
抗原
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