CYFIP1 抗体 (AA 1-270)
Quick Overview for CYFIP1 抗体 (AA 1-270) (ABIN6139306)
抗原
See all CYFIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-270
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序列
- MAAQVTLEDA LSNVDLLEEL PLPDQQPCIE PPPSSLLYQP NFNTNFEDRN AFVTGIARYI EQATVHSSMN EMLEEGQEYA VMLYTWRSCS RAIPQVKCNE QPNRVEIYEK TVEVLEPEVT KLMNFMYFQR NAIERFCGEV RRLCHAERRK DFVSEAYLIT LGKFINMFAV LDELKNMKCS VKNDHSAYKR AAQFLRKMAD PQSIQESQNL SMFLANHNKI TQSLQQQLEV ISGYEELLAD IVNLCVDYYE NRMYLTPSEK HMLLKVMGFG
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CYFIP1 (NP_055423.1).
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亚型
- IgG
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anti-Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) (AA 320-449) antibody
CYFIP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) (AA 524-558) antibodyCYFIP1 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB47040 unconjugated
anti-Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) antibodyKD Validated CYFIP1 适用: 人, 小鼠, 大鼠 WB, IF, ICC, FACS 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
- WB,1:1000 - 1:2000,IHC,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))
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别名
- CYFIP1
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背景
- Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity. Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity. May act as an invasion suppressor in cancers.,CYFIP1,P140SRA-1,SHYC,SRA-1,SRA1,CYFIP1
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分子量
- 51 kDa/94 kDa/145 kDa
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基因ID
- 23191
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UniProt
- Q7L576
抗原
-
