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Cathepsin L 抗体 (AA 114-333)

This anti-Cathepsin L antibody is a 兔 多克隆 antibody detecting Cathepsin L in WB 和 IF. Suitable for 人.
产品编号 ABIN6139235
发货至: 中国

Quick Overview for Cathepsin L 抗体 (AA 114-333) (ABIN6139235)

抗原

See all Cathepsin L (CTSL1) 抗体
Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Cathepsin L antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
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    AA 114-333

    序列

    APRSVDWREK GYVTPVKNQG QCGSCWAFSA TGALEGQMFR KTGRLISLSE QNLVDCSGPQ GNEGCNGGLM DYAFQYVQDN GGLDSEESYP YEATEESCKY NPKYSVANDT GFVDIPKQEK ALMKAVATVG PISVAIDAGH ESFLFYKEGI YFEPDCSSED MDHGVLVVGY GFESTESDNN KYWLVKNSWG EEWGMGGYVK MAKDRRNHCG IASAASYPTV

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 114-333 of human Cathepsin L/V/K/H (NP_001903.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

    别名

    CTSL

    背景

    The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.,CTSL,CATL,CTSL1,MEP,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Neuroscience,CTSL

    分子量

    37 kDa

    基因ID

    1514

    UniProt

    P07711

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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