Cathepsin H 抗体 (AA 23-335)
Quick Overview for Cathepsin H 抗体 (AA 23-335) (ABIN6139232)
抗原
See all Cathepsin H (CTSH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-335
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序列
- AELCVNSLEK FHFKSWMSKH RKTYSTEEYH HRLQTFASNW RKINAHNNGN HTFKMALNQF SDMSFAEIKH KYLWSEPQNC SATKSNYLRG TGPYPPSVDW RKKGNFVSPV KNQGACGSCW TFSTTGALES AIAIATGKML SLAEQQLVDC AQDFNNHGCQ GGLPSQAFEY ILYNKGIMGE DTYPYQGKDG YCKFQPGKAI GFVKDVANIT IYDEEAMVEA VALYNPVSFA FEVTQDFMMY RTGIYSSTSC HKTPDKVNHA VLAVGYGEKN GIPYWIVKNS WGPQWGMNGY FLIERGKNMC GLAACASYPI PLV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 23-335 of human CTSH (NP_004381.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cathepsin H (CTSH)
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别名
- CTSH
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背景
- The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.,CTSH,ACC-4,ACC-5,ACC4,ACC5,CPSB,Cell Biology & Developmental Biology,Cell Adhesion,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CTSH
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分子量
- 37 kDa
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基因ID
- 1512
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UniProt
- P09668
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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