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CTSC 抗体 (AA 25-134)

This anti-CTSC antibody is a 兔 多克隆 antibody detecting CTSC in WB. Suitable for 人.
产品编号 ABIN6139221
发货至: 中国

Quick Overview for CTSC 抗体 (AA 25-134) (ABIN6139221)

抗原

See all CTSC 抗体
CTSC (Cathepsin C (CTSC))

适用

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宿主

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克隆类型

  • 42
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多克隆

标记

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This CTSC antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 25-134

    序列

    DTPANCTYLD LLGTWVFQVG SSGSQRDVNC SVMGPQEKKV VVYLQKLDTA YDDLGNSGHF TIIYNQGFEI VLNDYKWFAF FKYKEEGSKV TTYCNETMTG WVHDVLGRNW

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 25-134 of human CTSC (NP_001805.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CTSC (Cathepsin C (CTSC))

    别名

    CTSC

    背景

    This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.,CTSC,CPPI,DPP-I,DPP1,DPPI,HMS,JP,JPD,PALS,PDON1,PLS,Cell Biology & Developmental Biology,Ubiquitin,CTSC

    分子量

    15 kDa/51 kDa

    基因ID

    1075

    UniProt

    P53634
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