CRYAA 抗体 (AA 1-173)
Quick Overview for CRYAA 抗体 (AA 1-173) (ABIN6139072)
抗原
See all CRYAA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-173
-
序列
- MDVTIQHPWF KRTLGPFYPS RLFDQFFGEG LFEYDLLPFL SSTISPYYRQ SLFRTVLDSG ISEVRSDRDK FVIFLDVKHF SPEDLTVKVQ DDFVEIHGKH NERQDDHGYI SREFHRRYRL PSNVDQSALS CSLSADGMLT FCGPKIQTGL DATHAERAIP VSREEKPTSA PSS
-
交叉反应
- 人, 小鼠, 大鼠, 斑马鱼
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human CRYAA (NP_000385.1).
-
亚型
- IgG
-
-
anti-Crystallin, alpha A (CRYAA) antibody
CRYAA 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-Crystallin, alpha A (CRYAA) antibodyCRYAA 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Crystallin, alpha A (CRYAA) (AA 77-106) antibodyCRYAA 适用: 人 WB 宿主: 兔 Polyclonal RB28544 unconjugated
anti-Crystallin, alpha A (CRYAA) antibodyCRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 unconjugated
anti-Crystallin, alpha A (CRYAA) antibody (HRP)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 HRP
anti-Crystallin, alpha A (CRYAA) antibody (FITC)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 FITC
anti-Crystallin, alpha A (CRYAA) antibody (Biotin)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 Biotin
anti-Crystallin, alpha A (CRYAA) antibody (PE)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 PE
anti-Crystallin, alpha A (CRYAA) antibody (APC)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 APC
anti-Crystallin, alpha A (CRYAA) antibody (PerCP)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 PerCP
-
-
应用备注
- WB,1:500 - 1:2000
-
说明
-
HIGH QUALITY
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- CRYAA (Crystallin, alpha A (CRYAA))
-
别名
- CRYAA
-
背景
- Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Defects in this gene cause autosomal dominant congenital cataract (ADCC).,CRYAA,CRYA1,CTRCT9,HSPB4,Signal Transduction,Neuroscience,Cell Type Marker,CRYAA
-
分子量
- 19 kDa
-
基因ID
- 1409
-
UniProt
- P02489
-
途径
- M Phase
抗原
-
