CREM 抗体 (AA 1-100)
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北京 101111
Quick Overview for CREM 抗体 (AA 1-100) (ABIN6139026)
抗原
See all CREM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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序列
- MSKCARKKYI KTNPRQMTME TVESQHDGSI TASLTESKSA HVQTQTGQNS IPALAQVAAI AETDESAESE GVIDSHKRRE ILSRRPSYRK ILNELSSDVP
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CREM (NP_853549.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CREM (CAMP Responsive Element Modulator (CREM))
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别名
- CREM
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背景
- This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.,CREM,CREM-2,ICER,hCREM-2,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,CREM
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分子量
- 11-38 kDa
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基因ID
- 1390
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UniProt
- Q03060
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途径
- Retinoic Acid Receptor Signaling Pathway
抗原
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