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COX IV 抗体 (AA 23-169)

This anti-COX IV antibody is a 兔 多克隆 antibody detecting COX IV in WB, IF 和 IP. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN6138910
发货至: 中国

Quick Overview for COX IV 抗体 (AA 23-169) (ABIN6138910)

抗原

See all COX IV (COX4I1) 抗体
COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

适用

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宿主

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克隆类型

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多克隆

标记

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This COX IV antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 抗原表位

    • 16
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    AA 23-169

    序列

    AHESVVKSED FSLPAYMDRR DHPLPEVAHV KHLSASQKAL KEKEKASWSS LSMDEKVELY RIKFKESFAE MNRGSNEWKT VVGGAMFFIG FTALVIMWQK HYVYGPLPQS FDKEWVAKQT KRMLDMKVNP IQGLASKWDY EKNEWKK

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 23-169 of human COX IV (NP_001852.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Han, Cao, Gao, Wang, Chen, Cai, Zhang, Hu, Ma, Gu, Ding: "ZIC1 acts a tumor suppressor in breast cancer by targeting survivin." in: International journal of oncology, Vol. 53, Issue 3, pp. 937-948, (2018) (PubMed).

    Hu, Nie, Chen, Xie, Fan, Wang, Long, Yan, Zhong, Yan: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." in: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).

  • 抗原

    COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

    别名

    COX4I1

    背景

    Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms.,COX4I1,COX IV-1,COX4,COX4-1,COXIV,COXIV-1,COX IV,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,COX4I1

    分子量

    19 kDa

    基因ID

    1327

    UniProt

    P13073

    途径

    Proton Transport
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