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COX10 抗体 (AA 1-160)

This anti-COX10 antibody is a 兔 多克隆 antibody detecting COX10 in WB. Suitable for 人.
产品编号 ABIN6138907
发货至: 中国

Quick Overview for COX10 抗体 (AA 1-160) (ABIN6138907)

抗原

See all COX10 抗体
COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))

适用

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宿主

  • 32
  • 2

克隆类型

  • 34
多克隆

标记

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This COX10 antibody is un-conjugated

应用范围

  • 25
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Western Blotting (WB)
  • 抗原表位

    • 8
    • 4
    • 3
    • 2
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    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-160

    序列

    MAASPHTLSS RLLTGCVGGS VWYLERRTIQ DSPHKFLHLL RNVNKQWITF QHFSFLKRMY VTQLNRSHNQ QVRPKPEPVA SPFLEKTSSG QAKAEIYEMR PLSPPSLSLS RKPNEKELIE LEPDSVIEDS IDVGKETKEE KRWKEMKLQV YDLPGILARL

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human COX10 (NP_001294.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))

    别名

    COX10

    背景

    Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.,COX10,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,COX10

    分子量

    27 kDa/48 kDa

    基因ID

    1352

    UniProt

    Q12887
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