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COMT 抗体 (AA 42-221)

This anti-COMT antibody is a 兔 多克隆 antibody detecting COMT in WB. Suitable for 人.
产品编号 ABIN6138867
发货至: 中国

Quick Overview for COMT 抗体 (AA 42-221) (ABIN6138867)

抗原

See all COMT 抗体
COMT (Catechol-O-Methyltransferase (COMT))

适用

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宿主

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克隆类型

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  • 30
多克隆

标记

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This COMT antibody is un-conjugated

应用范围

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  • 42
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Western Blotting (WB)
  • 抗原表位

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    AA 42-221

    序列

    VGDKKGKIVD AVIQEHQPSV LLELGAYCGY SAVRMARLLS PGARLITIEI NPDCAAITQR MVDFAGVKDK VTLVVGASQD IIPQLKKKYD VDTLDMVFLD HWKDRYLPDT LLLEECGLLR KGTVLLADNV ICPGAPDFLA HVRGSSCFEC THYQSFLEYR EVVDGLEKAI YKGPGSEAGP

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 42-221 of human COMT (NP_009294.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    COMT (Catechol-O-Methyltransferase (COMT))

    别名

    COMT

    背景

    Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.,COMT,HEL-S-98n,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Drug metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,COMT

    分子量

    24 kDa/30 kDa

    基因ID

    1312

    UniProt

    P21964

    途径

    Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
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