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COMP 抗体 (AA 20-160)

This 兔 多克隆 antibody specifically detects COMP in WB 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN6138864
发货至: 中国
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中国
北京 101111
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Room 801-803
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Quick Overview for COMP 抗体 (AA 20-160) (ABIN6138864)

抗原

See all COMP 抗体
COMP (Cartilage Oligomeric Matrix Protein (COMP))

适用

  • 50
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宿主

  • 67
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克隆类型

  • 69
  • 12
多克隆

标记

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This COMP antibody is un-conjugated

应用范围

  • 68
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 15
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    AA 20-160

    序列

    GQGQSPLGSD LGPQMLRELQ ETNAALQDVR ELLRQQVREI TFLKNTVMEC DACGMQQSVR TGLPSVRPLL HCAPGFCFPG VACIQTESGA RCGPCPAGFT GNGSHCTDVN ECNAHPCFPR VRCINTSPGF RCEACPPGYS G

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human COMP (NP_000086.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:10 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    COMP (Cartilage Oligomeric Matrix Protein (COMP))

    别名

    COMP

    背景

    The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).,COMP,EDM1,EPD1,MED,PSACH,THBS5,TSP5,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Cytoskeleton,Extracellular Matrix,Bone,Stem Cells,Mesenchymal Stem Cells,COMP

    分子量

    77 kDa/82 kDa

    基因ID

    1311

    UniProt

    P49747
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