COASY 抗体 (AA 345-564)
Quick Overview for COASY 抗体 (AA 345-564) (ABIN6138817)
抗原
See all COASY 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 345-564
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序列
- LRPPYERPEL PTCLYVIGLT GISGSGKSSI AQRLKGLGAF VIDSDHLGHR AYAPGGPAYQ PVVEAFGTDI LHKDGIINRK VLGSRVFGNK KQLKILTDIM WPIIAKLARE EMDRAVAEGK RVCVIDAAVL LEAGWQNLVH EVWTAVIPET EAVRRIVERD GLSEAAAQSR LQSQMSGQQL VEQSHVVLST LWEPHITQRQ VEKAWALLQK RIPKTHQALD
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 345-564 of human CoA synthase (COASY) (NP_079509.5).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- COASY (CoA Synthase (COASY))
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别名
- COASY
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背景
- Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.,COASY,DPCK,NBIA6,NBP,PPAT,UKR1,pOV-2,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,COASY
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分子量
- 62 kDa/65 kDa
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基因ID
- 80347
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UniProt
- Q13057
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途径
- Ribonucleoside Biosynthetic Process
抗原
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