CNOT7 抗体 (AA 90-160)
Quick Overview for CNOT7 抗体 (AA 90-160) (ABIN6138783)
抗原
See all CNOT7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 90-160
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序列
- PGTSTWQFNF KFNLTEDMYA QDSIELLTTS GIQFKKHEEE GIETQYFAEL LMTSGVVLCE GVKWLSFHSG Y
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 90-160 of human CNOT7 (NP_037486.2).
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亚型
- IgG
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应用备注
- WB,1:200 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))
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别名
- CNOT7
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背景
- The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.,CNOT7,CAF-1,CAF1,Caf1a,hCAF-1,Epigenetics & Nuclear Signaling,CNOT7
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分子量
- 28 kDa/32 kDa
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基因ID
- 29883
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UniProt
- Q9UIV1
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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