CIRBP 抗体 (AA 1-172)
Quick Overview for CIRBP 抗体 (AA 1-172) (ABIN6138628)
抗原
See all CIRBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-172
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序列
- MASDEGKLFV GGLSFDTNEQ SLEQVFSKYG QISEVVVVKD RETQRSRGFG FVTFENIDDA KDAMMAMNGK SVDGRQIRVD QAGKSSDNRS RGYRGGSAGG RGFFRGGRGR GRGFSRGGGD RGYGGNRFES RSGGYGGSRD YYSSRSQSGG YSDRSSGGSY RDSYDSYATH NE
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CIRBP (NP_001271.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:10 - 1:100
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CIRBP (Cold Inducible RNA Binding Protein (CIRBP))
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别名
- CIRBP
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背景
- Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity. Promotes assembly of stress granules (SGs, when overexpressed.,CIRBP,CIRP,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Cell Cycle,CIRBP
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分子量
- 18 kDa/26 kDa/28 kDa
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基因ID
- 1153
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UniProt
- Q14011
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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