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CDK5 抗体 (AA 1-292)

This anti-CDK5 antibody is a 兔 多克隆 antibody detecting CDK5 in WB, IP 和 IF. Suitable for 人.
产品编号 ABIN6138319
发货至: 中国

Quick Overview for CDK5 抗体 (AA 1-292) (ABIN6138319)

抗原

See all CDK5 抗体
CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

适用

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宿主

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克隆类型

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多克隆

标记

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This CDK5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-292

    序列

    MQKYEKLEKI GEGTYGTVFK AKNRETHEIV ALKRVRLDDD DEGVPSSALR EICLLKELKH KNIVRLHDVL HSDKKLTLVF EFCDQDLKKY FDSCNGDLDP EIVKSFLFQL LKGLGFCHSR NVLHRDLKPQ NLLINRNGEL KLADFGLARA FGIPVRCYSA EVVTLWYRPP DVLFGAKLYS TSIDMWSAGC IFAELANAGR PLFPGNDVDD QLKRIFRLLG TPTEEQWPSM TKLPDYKPYP MYPATTSLVN VVPKLNATGR DLLQNLLKCN PVQRISAEEA LQHPYFSDFC PP

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human CDK5 (NP_004926.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:10 - 1:100,IP,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

    别名

    CDK5

    背景

    This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.,CDK5,LIS7,PSSALRE,Cancer,Signal Transduction,G protein signaling,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,Cytokines,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Dopamine Signaling in Parkinson's Disease,Neurodegenerative Diseases Markers,CDK5

    分子量

    29 kDa/33 kDa

    基因ID

    1020

    UniProt

    Q00535

    途径

    Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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