CD38 抗体 (AA 46-300)
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北京 101111
Quick Overview for CD38 抗体 (AA 46-300) (ABIN6138177)
抗原
See all CD38 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 46-300
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序列
- WRQQWSGPGT TKRFPETVLA RCVKYTEIHP EMRHVDCQSV WDAFKGAFIS KHPCNITEED YQPLMKLGTQ TVPCNKILLW SRIKDLAHQF TQVQRDMFTL EDTLLGYLAD DLTWCGEFNT SKINYQSCPD WRKDCSNNPV SVFWKTVSRR FAEAACDVVH VMLNGSRSKI FDKNSTFGSV EVHNLQPEKV QTLEAWVIHG GREDSRDLCQ DPTIKELESI ISKRNIQFSC KNIYRPDKFL QCVKNPEDSS CTSEI
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 46-300 of human CD38 (NP_001766.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CD38
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背景
- The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.,CD38,ADPRC 1,ADPRC1,Cancer,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CD38
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分子量
- 13 kDa/34 kDa
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基因ID
- 952
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UniProt
- P28907
抗原
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