CCM2 抗体 (AA 1-300)
Quick Overview for CCM2 抗体 (AA 1-300) (ABIN6138069)
抗原
See all CCM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-300
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序列
- MEEEGKKGKK PGIVSPFKRV FLKGEKSRDK KAHEKVTERR PLHTVVLSLP ERVEPDRLLS DYIEKEVKYL GQLTSIPGYL NPSSRTEILH FIDNAKRAHQ LPGHLTQEHD AVLSLSAYNV KLAWRDGEDI ILRVPIHDIA AVSYVRDDAA HLVVLKTAQD PGISPSQSLC AESSRGLSAG SLSESAVGPV EACCLVILAA ESKVAAEELC CLLGQVFQVV YTESTIDFLD RAIFDGASTP THHLSLHSDD SSTKVDIKET YEVEASTFCF PESVDVGGAS PHSKTISESE LSASATELLQ
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CCM2 (NP_113631.1).
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亚型
- IgG
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anti-Cerebral Cavernous Malformation 2 (CCM2) (Internal Region) antibody
Verified CCM2 适用: 人, 大鼠 WB, IF, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) antibodyCCM2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-300) antibodyCCM2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 2-100) antibodyCCM2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) antibodyCCM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444), (N-Term) antibodyCCM2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
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别名
- CCM2
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背景
- This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.,CCM2,C7orf22,OSM,PP10187,Signal Transduction,Neuroscience,CCM2
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分子量
- 39 kDa/42 kDa/48 kDa/51 kDa
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基因ID
- 83605
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UniProt
- Q9BSQ5
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途径
- Cell-Cell Junction Organization
抗原
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