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CARD11 抗体 (AA 985-1154)

This anti-CARD11 antibody is a 兔 多克隆 antibody detecting CARD11 in WB 和 IF. Suitable for 人.
产品编号 ABIN6137939
发货至: 中国

Quick Overview for CARD11 抗体 (AA 985-1154) (ABIN6137939)

抗原

See all CARD11 抗体
CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

适用

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宿主

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克隆类型

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多克隆

标记

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This CARD11 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 985-1154

    序列

    AKTLVQRLLN SGGAMEFTIC KSDIVTRDEF LRRQKTETII YSREKNPNAF ECIAPANIEA VAAKNKHCLL EAGIGCTRDL IKSNIYPIVL FIRVCEKNIK RFRKLLPRPE TEEEFLRVCR LKEKELEALP CLYATVEPDM WGSVEELLRV VKDKIGEEQR KTIWVDEDQL

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 985-1154 of human CARD11 (NP_115791.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

    别名

    CARD11

    背景

    The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.,CARD11,BENTA,BIMP3,CARMA1,IMD11,PPBL,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Caspases,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,CARD11

    分子量

    133 kDa

    基因ID

    84433

    UniProt

    Q9BXL7

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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