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C8orf4 抗体 (AA 1-106)

The 兔 多克隆 anti-C8orf4 antibody (ABIN6137787) specifically detects C8orf4 in WB 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN6137787
发货至: 中国
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Quick Overview for C8orf4 抗体 (AA 1-106) (ABIN6137787)

抗原

See all C8orf4 抗体
C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))

适用

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宿主

  • 27

克隆类型

  • 27
多克隆

标记

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This C8orf4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 1
    • 1
    • 1
    AA 1-106

    序列

    MKAKRSHQAI IMSTSLRVSP SIHGYHFDTA SRKKAVGNIF ENTDQESLER LFRNSGDKKA EERAKIIFAI DQDVEEKTRA LMALKKRTKD KLFQFLKLRK YSIKVH

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human C8orf4 (NP_064515.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))

    别名

    C8orf4

    背景

    This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.,C8orf4,TC-1,TC1,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Stem Cells,C8orf4

    分子量

    12 kDa

    基因ID

    56892

    UniProt

    Q9NR00
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