Bestrophin 1 抗体 (AA 376-585)
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北京 101111
Quick Overview for Bestrophin 1 抗体 (AA 376-585) (ABIN6137534)
抗原
See all Bestrophin 1 (BEST1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 376-585
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序列
- QPNQEDEEDA HAGIIGRFLG LQSHDHHPPR ANSRTKLLWP KRESLLHEGL PKNHKAAKQN VRGQEDNKAW KLKAVDAFKS APLYQRPGYY SAPQTPLSPT PMFFPLEPSA PSKLHSVTGI DTKDKSLKTV SSGAKKSFEL LSESDGALME HPEVSQVRRK TVEFNLTDMP EIPENHLKEP LEQSPTNIHT TLKDHMDPYW ALENRDEAHS
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 376-585 of human BEST1 (NP_004174.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Bestrophin 1 (BEST1)
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别名
- BEST1
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背景
- This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.,BEST1,ARB,BEST,BMD,RP50,TU15B,VMD2,Cell Biology & Developmental Biology,Cell Adhesion,Neuroscience,BEST1
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分子量
- 57 kDa/67 kDa/69 kDa
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基因ID
- 7439
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UniProt
- O76090
抗原
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