BCCIP 抗体 (AA 1-314)
Quick Overview for BCCIP 抗体 (AA 1-314) (ABIN6137485)
抗原
See all BCCIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-314
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序列
- MASRSKRRAV ESGVPQPPDP PVQRDEEEEK EVENEDEDDD DSDKEKDEED EVIDEEVNIE FEAYSLSDND YDGIKKLLQQ LFLKAPVNTA ELTDLLIQQN HIGSVIKQTD VSEDSNDDMD EDEVFGFISL LNLTERKGTQ CVEQIQELVL RFCEKNCEKS MVEQLDKFLN DTTKPVGLLL SERFINVPPQ IALPMYQQLQ KELAGAHRTN KPCGKCYFYL LISKTFVEAG KNNSKKKPSN KKKAALMFAN AEEEFFYEKA ILKFNYSVQE ESDTCLGGKW SFDDVPMTPL RTVMLIPGDK MNEIMDKLKE YLSV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-314 of human BCCIP (NP_510868.1).
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亚型
- IgG
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anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (C-Term) antibody
BCCIP 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-322) antibodyBCCIP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-314) antibodyBCCIP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (C-Term) antibodyBCCIP 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 210-314) antibodyBCCIP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) antibodyBCCIP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
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别名
- BCCIP
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背景
- This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.,BCCIP,TOK-1,TOK1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RNA Binding,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Immunology & Inflammation,Cytokines,BCCIP
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分子量
- 33 kDa/35 kDa/36 kDa
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基因ID
- 56647
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UniProt
- Q9P287
抗原
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