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AFT1 抗体 (AA 1-210)

This anti-AFT1 antibody is a 兔 多克隆 antibody detecting AFT1 in WB 和 IP. Suitable for 人.
产品编号 ABIN6137228
发货至: 中国

Quick Overview for AFT1 抗体 (AA 1-210) (ABIN6137228)

抗原

See all AFT1 抗体
AFT1 (Activating Transcription Factor 1 (AFT1))

适用

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宿主

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克隆类型

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多克隆

标记

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This AFT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    AA 1-210

    序列

    MEDSHKSTTS ETAPQPGSAV QGAHISHIAQ QVSSLSESEE SQDSSDSIGS SQKAHGILAR RPSYRKILKD LSSEDTRGRK GDGENSGVSA AVTSMSVPTP IYQTSSGQYI AIAPNGALQL ASPGTDGVQG LQTLTMTNSG STQQGTTILQ YAQTSDGQQI LVPSNQVVVQ TASGDMQTYQ IRTTPSATSL PQTVVMTSPV TLTSQTTKTD

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human ATF1 (NP_005162.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IP,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    AFT1 (Activating Transcription Factor 1 (AFT1))

    别名

    ATF1

    背景

    This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.,ATF1,EWS-ATF1,FUS/ATF-1,TREB36,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,ATF1

    分子量

    15 kDa/29 kDa

    基因ID

    466

    UniProt

    P18846

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
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