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ASCC2 抗体 (AA 488-757)

ASCC2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6137169
发货至: 中国
  • 抗原 See all ASCC2 抗体
    ASCC2 (Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2))
    抗原表位
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 488-757
    适用
    • 23
    • 13
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 16
    • 7
    克隆类型
    • 19
    • 4
    多克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASCC2 antibody is un-conjugated
    应用范围
    • 16
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    LACLEYYHYD PEQVINNILE ERLAPTLSQL DRNLDREMKP DPTPLLTSRH NVFQNDEFDV FSRDSVDLSR VHKGKSTRKE ENTRSLLNDK RAVAAQRQRY EQYSVVVEEV PLQPGESLPY HSVYYEDEYD DTYDGNQVGA NDADSDDELI SRRPFTIPQV LRTKVPREGQ EEDDDDEEDD ADEEAPKPDH FVQDPAVLRE KAEARRMAFL AKKGYRHDSS TAVAGSPRGH GQSRETTQER RKKEANKATR ANHNRRTMAD RKRSKGMIPS
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 488-757 of human ASCC2 (NP_115580.2).
    亚型
    IgG
    Top Product
    Discover our top product ASCC2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ASCC2 (Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2))
    别名
    ASCC2 (ASCC2 产品)
    别名
    MGC63666 antibody, zgc:63666 antibody, ASCC2 antibody, ascc2 antibody, asc1p100 antibody, ASC1p100 antibody, p100 antibody, 1700011I11Rik antibody, 2610034L15Rik antibody, AI482016 antibody, AW046480 antibody, RGD1561422 antibody, activating signal cointegrator 1 complex subunit 2 antibody, activating signal cointegrator 1 complex subunit 2 S homeolog antibody, ascc2 antibody, ASCC2 antibody, MCYG_08331 antibody, ascc2.S antibody, Ascc2 antibody
    背景
    Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. Involved in activation of the ribosome quality control (RQC pathway, a pathway that degrades nascent peptide chains during problematic translation. As part of the ribosome quality control trigger (RQT complex, recognizes ZNF598-dependent ubiquitination of stalled ribosomes (By similarity.,ASCC2,ASC1p100,p100,Signal Transduction,ASCC2
    分子量
    41 kDa/77 kDa/86 kDa
    基因ID
    84164
    UniProt
    Q9H1I8
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